Services for Food and Nutrition

Food | Nutrition: PhytoChemical Analysis & Health Function Investigation

Since 1997 Brunswick Labs helps companies like PepsiCo, Kraft Foods, Campbell's, and Johnson & Johnson develop better products. Our three-stage approach allows small investments become large discoveries that matter to your customers: We help you make healthier and more marketable products by substantiating health benefit claims through phytonutrient analysis, clinical, and preclinical studies.

Stage 1  Phytonutrient ID and Quantification

  • Antioxidant and Other Nutrient Analysis: ORAC, ORAC 6.0 and more
  • Phytochemical profiling via LC-MS/MS and HPLC

Stage 2   Human Cells-Based Bioassays to assess health function potentials

  • Bioavailability, BioAbsorption, and BioUptake study via Caco-2 human intestinal cells
  • Anti-inflammatory via LOX, COX, TNF-alpha, NFkB, Interleukins (ILs), and PGE2 as biomarkers
  • Oxidative Stress Analysis for biological samples
  • Antioxidation effect in a biological system   Nrf2, Cellular Antioxidant Assay (CAA)   
  • Diabetes and Weight Management   insulin secretion, insulin receptor activity, glucose uptake, glucose metabolism, and carbohydrate digestion as biomarkers
  • Immune Boost via cellular interleukins (ILs) expression
  • Anti-allergy property via Nrf2 expression
  • Mitochondria Health  mitochondrial ROS level
  • Detoxification and Liver Function   Phase I and Phase II liver enzymes, liver function biomarkers in serum
  • Energy metabolism investigation via human cells  
  • Anti-cancer Function evaluation: cancer cell viability, proliferation, apoptosis, and invasion as biomarkers 
  • Anti-aging  SIRT-1, telomerase activity as biomarkers
  • Neurite outgrowth assay  assesses the neurite outgrowth using a widely used neuronal model based on neuron growth factor (NGF)-stimulated mammalian cells
  • Preclinical for Skin Care Products  UV protection, melanin (age spot) inhibition, anti-aging, anti-inflammatory

Stage 3  Clinical Studies and Preclinical Studies

  • Fully integrated clinical studies for Oxidative Stress Analysis, Inflammation Reduction, Weight/Diabetes Management, Digestive Efficacy, and other health functions
  • ADME, Toxicity, PKPD studies: in vitro and in vivo 
  • Bioanalytical Services: biomarker identificaiton, bioassay development, active ingredient ID and quantification

 

Science Backed Marketing · Product Certification

  • Brunswick Labs Product Testing Certification is nutritional testing validation system that supports marketing via scientific research. Press releases, SEO, social media, a packaging/promotion certificaiton seal, subscription channels, and an exclusive website (blcert.com) showcase certified products and their test results

Investigative Rsearch Services   We combine our in-depth knowledge with sophisticated analytical techniques and bioassay investigation to meet your objectives