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HOME  >  PHARMACEUTICS  >  IN VIVO MODELS  >  PARKINSON'S DISEASE MODEL  >  6-OHDA RAT PARKINSON'S DISEASE MODEL

6-OHDA rat Parkinson’s disease model in rat:
  • Pathology criteria include: Tyrosine Hydroxylase (TH) immuncytochemistry (study substantia nigra neurons) and DA neurons count (labeled with retrograde tracer, fluorogold).
  • Behavior testing including: rotation testing, reaching task, forelimb asymmetry test (also known as the cylinder test), tactile placing.
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